Hepatoid adenocarcinoma of the gallbladder with production of alpha-fetoprotein

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Hepatoid adenocarcinoma of the gallbladder with production of alpha-fetoprotein

Hepatoid adenocarcinoma (HAC) is a tumor with aberrant hepatocellular differentiation that occurs in extrahepatic organs. HAC of the gallbladder is rare, and cases of alpha-fetoprotein production are extremely rare. A 61-year-old man was diagnosed with gallbladder adenocarcinoma after laparoscopic cholecystectomy. A radical operation including resection of liver bed and lymph node dissection wa...

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Alpha-fetoprotein production by a hepatoid adenocarcinoma of the uterus.

A case of a 62 year old Japanese woman with an endometrial adenocarcinoma producing alpha-fetoprotein (AFP) is described. Microscopically, the tumour was composed of a major medullary portion and a minor tubular adenocarcinoma which had invaded the myometrium, the myometrial lymphatics and blood vessels. Neoplastic cells in the medullary portion were polygonal with glycogen-rich cytoplasm. Vasc...

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Alpha-fetoprotein-producing hepatoid adenocarcinoma of the gallbladder: a case report and review of literature

Hepatoid adenocarcinoma (HAC) is an uncommon type of malignancy in extrahepatic tissues. It was named for its histopathological resemblance of hepatocellular carcinoma, the most common form of liver cancer. The occurrence of HAC in the gallbladder is very low, and tumours that produce alpha-fetoprotein are even rarer. Clinically, it is usually diagnosed histopathologically; and the prognosis is...

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Hepatoid adenocarcinoma of the gallbladder

Hepatoid adenocarcinoma is a rare variant of extrahepatic adenocarcinoma which behaves like hepatocellular carcinoma in morphology and functionality. We present a rare case of hepatoid adenocarcinoma of the gallbladder which invades deeply the liver bed, in a 59-year-old woman. Histologically, most of the mass in the gallbladder was composed of cells with eosinophilic cytoplasm arranged in a tr...

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Carcinosarcoma of the Uterine Corpus with Alpha-Fetoprotein-Producing Hepatoid Adenocarcinoma: A Report of Two Cases

We report two cases of uterine carcinosarcoma associated with alpha-fetoprotein (AFP)-producing hepatoid adenocarcinoma. Samples were obtained from two women aged 63 and 82 years. Serum AFP levels of the two samples were 10,131 and 401 ng/ml, respectively. Histologically, in both cases the tumor cells were composed of hepatoid adenocarcinoma component and sarcoma component including rhabdomyosa...

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ژورنال

عنوان ژورنال: Journal of the Korean Surgical Society

سال: 2011

ISSN: 2233-7903

DOI: 10.4174/jkss.2011.80.6.440